Europa Universalis IV
Europa Universalis 4 is a grand strategy game made by Paradox Interactive set in the age of exploration and enlightenment, from 1444 to sometime around 1800. A sequel to Europa Universalis 3 which I have played multiple hundred hours of, it is a game I am highly excited for.
In the game you chose any country on the face of the earth during the time period, and lead it in conquest, trade, exploration, diplomacy, and/or getting repeatedly wrecked by rebels and probably france. EU4 sees changes and improvements in a number of areas over it's predecessor, such as trade (individual centers of trades decentralized into areas and the change from local trade only to controlling the flow of goods from the far east and new world into Europe), the economy (a larger reliance on loans to finance wars, no more minting, monthly income instead of monthly expenses and yearly income) technology (monarch points instead of invested money) and just about everything else in some way.
The big change is monarch points. Your monarch (or president/doge/etc. if you're playing a filthy republic) generates points, based on how skilled they are in 3 different areas (administration, diplomacy, military) you use these points for everything. Creating a core? Administration power. Offering a peace deal? Diplomatic power. Recruiting a general? Military power. The thing is, there are tons of other uses for these resources too, and you also need a large number of them to advance technologily. Knowing when to horde and when to spend your points is going to be important.